CREDIT : 3 CREDITS
The course will emphasize on the basic design of a fermenter which include the principle and concept of the process control involved. This course introduces two basic concepts: (i) reaction mechanisms and kinetic rate expressions for homogeneous and heterogeneous reacting systems, including enzyme catalyzed reactions and cell growth kinetics, and (ii) reactor design for the homogeneous reaction systems. The design principles for ideal homogeneous reactors are introduced, followed by the concept of RTD (residence time distribution) to diagnose and account for the non-idealities in flow patterns. For heterogeneous reactions, the role of transport (diffusion) effects, Thiele modulus, and catalyst effectiveness factor are introduced.
1. Describe different types of bioreactors with their specifications and and stndard operations
2. Illustrate shematic diagrams for specific bioreactors with their specific functionality
3. Analyze kinetic parameters of different fermentation process and choose suitable bioreactor for the growth of organism and product formation at industrial level.
4. Design a hypothetical scale up bioreactor based on geometric similarities for industrial biotechnology application
5. Discuss and calculate the important parameter to be control in designing a bioreactor
6. Discuss related ethical issues in bioprocess technology including rules and regulation as well as impact to human and environment.
7. Demonstrate the functions and applications of the designed hypothetical scale up bioreactor in a schematic diagram